Bioactivity:

PTC-209 HBr is the hydrobromide salt of PTC-209, which is a potent and selective BMI-1 inhibitor with IC50 of 0.5 _M, and results in irreversible reduction of cancer-initiating cells (CICs).

CAS nr:

1217022-63-3

Purity:

98%

Molecular Weight:

576,1

SMILES:

Br.COC1=CC(Br)=C(NC2=NC(=CS2)C2=C(C)N=C3N=CC=CN23)C(Br)=C1

Formula:

C17H13Br2N5OS�HBr

Pathway:

DNA Damage/DNA Repair,Cell Cycle/Checkpoint,Autophagy

Target:

BMI-1,BMI-1,Autophagy