Bioactivity:

PF-543, a novel sphingosine-competitive inhibitor of SphK1, inhibits SphK1 with IC50 and Ki of 2.0 nM and 3.6 nM.

CAS nr:

1415562-82-1

Purity:

98%

Molecular Weight:

465,6

SMILES:

Cc1cc(CS(=O)(=O)c2ccccc2)cc(OCc2ccc(CN3CCC[C@@H]3CO)cc2)c1

Formula:

C27H31NO4S

Pathway:

GPCR/G Protein,GPCR/G Protein,Autophagy,Apoptosis

Target:

LPL Receptor,S1P Receptor,Autophagy,Apoptosis