Bioactivity:

Mcl1-IN-12 has anti-tumor activity.It is a selective Mcl-1 inhibitor, less potent at Bcl-2, with Kis of 0.29 and 3.1 _M, respectively.

CAS nr:

2042211-12-9

Purity:

98%

Molecular Weight:

803

SMILES:

O=C(NS(=O)(C1=CC=C(NCCSC2=CC=CC=C2)C([N+]([O-])=O)=C1)=O)C3=CC=C(NC(C(C=C4)=CC=C4C(C5=C(C)C=C(C(C)(C)CCC6(C)C)C6=C5)=C)=O)C=C3

Formula:

C45H46N4O6S2

Pathway:

Apoptosis

Target:

BCL