Bioactivity:

Smurf1-IN-A01 is a ubiquitin ligase Smad ubiquitination regulatory factor-1 inhibitor (kd: 3.664 nM). It increases BMP-2 responsiveness by inhibiting Smurf1-mediated Smad1/5 degradation.

CAS nr:

1007647-73-5

Purity:

98%

Molecular Weight:

512,93

SMILES:

CC1=CC=NN1C2=CC=C(C=C2)C(=O)N3CCN(CC3)S(=O)(=O)C4=CC(=C(C=C4)Cl)C(F)(F)F

Formula:

C22H20ClF3N4O3S

Pathway:

Others

Target:

Others