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Bioactivity:
Compound 401 is a synthetic DNA-PK inhibitor (IC50 = 0.28 _M) that also targets mTOR but not PI3K.
CAS nr:
168425-64-7
Purity:
98%
Molecular Weight:
281,31
SMILES:
C1COCCN1c1cc(=O)n2ccc3ccccc3c2n1
Formula:
C16N15H3O2
Pathway:
PI3K/Akt/mTOR signaling,DNA Damage/DNA Repair
Target:
DNA-PK,DNA-PK