Bioactivity:

Centrinone (LCR-263) is a reversible inhibitor of polo-like kinase 4 (PLK4; Ki:0.16 nM).

CAS nr:

1798871-30-3

Purity:

98%

Molecular Weight:

633,65

SMILES:

CC1=CC(NC2=NC(SC3=CC=C(S(=O)(CC4=CC=CC([N+]([O-])=O)=C4F)=O)C=C3F)=NC(N5CCOCC5)=C2OC)=NN1

Formula:

C26H25F2N7O6S2

Pathway:

Cell Cycle/Checkpoint,Cell Cycle/Checkpoint,Chromatin/Epigenetic

Target:

PLK,Aurora Kinase,Aurora Kinase