Bioactivity:

GCN2-IN-6 is also a eIF2_ kinase PERK inhibitor with an IC50 of 0.26 nM (in enzymatic assay) and 230 nM (in cells).�GCN2-IN-6 �is a potent, and orally available GCN2 inhibitor confirmed by in-house enzymatic (IC50 of 1.8 nM) and cellular assays (IC50 of 9

CAS nr:

2183470-09-7

Purity:

98%

Molecular Weight:

485,29

SMILES:

O=S(C1=CC(Cl)=CC(CO)=C1Cl)(NC2=CC=C(F)C(C#CC3=CN=C(N)N=C3)=C2F)=O

Formula:

C19H12Cl2F2N4O3S

Pathway:

Others,Apoptosis

Target:

Others,PERK