BGG463 T4618
Specifications
| 1mg/5mg/10mg/25mg/50mg/100mg |
Bioactivity:
BGG463 can inhibit c-ABL-T334I, BCR-ABL and BCR-ABL-T315I variants with a 50% inhibitory concentration (IC50) of 0.25 _M, 0.09 _M and 0.590 _M, respectively.
CAS nr:
890129-26-7
Purity:
98%
Molecular Weight:
578,6
SMILES:
CC(=O)Nc1cc(ncn1)Oc2ccc3c(c2)cccc3C(=O)Nc5ccc(CN4CCN(C)CC4)c(c5)C(F)(F)F
Formula:
C30H29F3N6O3
Pathway:
Angiogenesis,Tyrosine Kinase/Adaptors,Cytoskeletal Signaling,Cell Cycle/Checkpoint
Target:
Bcr-Abl,Bcr-Abl,Bcr-Abl,CDK
