Bioactivity:

Propargyl-PEG4-acid is a PEG-based PROTAC linker can be used in the synthesis of BTK-IAP PROTACs Ibrutinib -based PROTAC 2 and an analogue PROTAC 3. PROTAC 3 causes BTK degradation with a DC50 of 200 nM in THP-1 cells[1].

CAS nr:

1415800-32-6

Purity:

98%

Molecular Weight:

260,28

SMILES:

C#CCOCCOCCOCCOCCC(O)=O

Formula:

C12H20O6

Pathway:

Others

Target:

Others