Bioactivity:

FR 167653 free base is an orally active p38 MAPK inhibitor and is effective in treating inflammation, relieving trauma, and ischemia-reperfusion injury in vivo. It also is a potent suppressor of TNF-_ and IL-1_ production via specific inhibition of p38 MA

CAS nr:

158876-65-4

Purity:

98%

Molecular Weight:

427,43

SMILES:

O=C(N1NC2=C(C3=CC=NC=C3)C(C4=CC=C(F)C=C4)=NN2CC1)C(C5=CC=CC=C5)=O

Formula:

C24H18FN5O2

Pathway:

Others

Target:

Others