Bioactivity:

EG00229 selectively inhibits VEGF-A binding to NRP1 b1 domain with an IC50 of 3 _M, but has no effect on VEGFA binding to VEGFR-1 and VEGFR-2. EG00229 is a neuropilin 1 (NRP1) receptor antagonist.

CAS nr:

1210945-69-9

Purity:

98%

Molecular Weight:

611,6

SMILES:

N=C(N)NCCC[C@@H](C(O)=O)NC(C1=C(NS(=O)(C2=CC=CC3=NSN=C32)=O)C=CS1)=O.O=C(O)C(F)(F)F

Formula:

C19H20F3N7O7S3

Pathway:

Others

Target:

Others