Bioactivity:

Evacetrapib (LY2484595) is a potent and selective inhibitor of CETP with IC50 of 5.5 nM, elevates HDL cholesterol without increases in aldosterone or blood pressure. Phase 3.

CAS nr:

1186486-62-3

Purity:

98%

Molecular Weight:

638,65

SMILES:

[H][C@]1(CN2CCC[C@]([H])(N(CC3=CC(=CC(=C3)C(F)(F)F)C(F)(F)F)C3=NN(C)N=N3)C3=C2C(C)=CC(C)=C3)CC[C@@]([H])(CC1)C(O)=O

Formula:

C31H36F6N6O2

Pathway:

Metabolism

Target:

CETP