Bioactivity:

CM-414 is a dual inhibitor of HDACs and PDE5 for the Treatment of Alzheimer�s Disease (IC50 values of 60 nM, 310 nM, 490 nM, 322 nM, and 91 nM against PDE5, HDAC1, HDAC2, HDAC3, and HDAC6, respectively). Chronic treatment of Tg2576 mice with CM-414 dimini

CAS nr:

1624792-70-6

Purity:

98%

Molecular Weight:

439,52

SMILES:

CCOC1=C(C2=NC(C(CCC)=NN3C)=C3C(N2)=O)C=C(CC4CC(C(NO)=O)C4)C=C1

Formula:

C23H29N5O4

Pathway:

Target: