Bioactivity:

PFI-2 is an effective, specific and cell-active lysine methyltransferase SETD7 inhibitor (Ki/IC50: 0.33/2 nM), 1000-fold selectivity over other methyltransferases and other non-epigenetic targets.

CAS nr:

1627676-59-8

Purity:

98%

Molecular Weight:

499,52

SMILES:

Fc1cc(cc2CCNCc12)S(=O)(=O)N[C@H](Cc1cccc(c1)C(F)(F)F)C(=O)N1CCCC1

Formula:

C23H25F4N3O3S

Pathway:

Chromatin/Epigenetic

Target:

Histone Methyltransferase