Bioactivity:

Vofopitant dihydrochloride is a selective and orally available antagonist of tachykinin neurokinin 1(NK1) receptor (pKi: 9.5 and 10.6 in rat and human membranes respectively) and is a potential broad-spectrum anti-emetic agent.

CAS nr:

168266-51-1

Purity:

98%

Molecular Weight:

505,36

SMILES:

COC1=C(CN[C@H]2CCCN[C@H]2C3=CC=CC=C3)C=C(N4N=NN=C4C(F)(F)F)C=C1.[H]Cl.[H]Cl

Formula:

C21H25Cl2F3N6O

Pathway:

GPCR/G Protein,Neuroscience

Target:

Neurokinin receptor,Neurokinin receptor