Bioactivity:

PPY A is an effective inhibitor of T315l mutant and wild-type Abl kinases (IC50: 9 and 20 nM, respectively). PPY A also inhibits the growth of cells transformed with either the Bcr-Abl T315l mutant or wild-type Bcr-Abl gene.

CAS nr:

875634-01-8

Purity:

98%

Molecular Weight:

372,42

SMILES:

CN(C)C(=O)C1=CN=CC(=C1)C2=CN=C3C(=C2)C(=CN3)C4=CC=CC=C4OC

Formula:

C22H20N4O2

Pathway:

Others

Target:

Others