Bioactivity:

Buddlejasaponin IV has analgesic and anti-inflammatory effects, the inhibitions of the expressions of iNOS, COX-2, TNF-alpha, IL-1beta and IL-6 by blocking NF-kappaB activation.

CAS nr:

139523-30-1

Purity:

98%

Molecular Weight:

943,12

SMILES:

C[C@@H]1[C@@H]([C@@H]([C@H]([C@@H](O1)O[C@H]2CC[C@]3([C@H]([C@]2(C)CO)CC[C@@]4([C@@H]3C=C[C@@]56[C@]4(C[C@@H]([C@@]7([C@H]5CC(CC7)(C)C)CO6)O)C)C)C)O[C@H]8[C@@H]([C@H]([C@@H]([C@H](O8)CO)O)O)O)O[C@H]9[C@@H]([C@H]([C@@H]([C@H](O9)CO)O)O)O)O

Formula:

C48H78O18

Pathway:

Cell Cycle/Checkpoint,DNA Damage/DNA Repair,Chromatin/Epigenetic,Cytoskeletal Signaling,PI3K/Akt/mTOR signaling

Target:

Chk,PARP,PARP,Akt,Akt