Bioactivity:

MPT0B206 is a novel tubulin polymerization inhibitor. MPT0B206 induced G2/M cell cycle arrest and the appearance of the mitotic marker MPM-2 in K562 and K562R cells, which is associated with the upregulation of cyclin B1 and the dephosphorylation of Cdc2.

CAS nr:

T28092

Purity:

98%

Molecular Weight:

332,37

SMILES:

O=CNC1=CC=CC2=C1N(S(=O)(C3=CC=C(OC)C=C3)=O)CC2

Formula:

C16H16N2O4S

Pathway:

Target: