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Bioactivity:
PND-1186 (VS-4718) is a reversible and specific FAK inhibitor (IC50: 1.5 nM).
CAS nr:
1061353-68-1
Purity:
98%
Molecular Weight:
501,5
SMILES:
CNC(=O)c1ccccc1Nc1cc(Nc2ccc(cc2OC)N2CCOCC2)ncc1C(F)(F)F
Formula:
C25H26F3N5O3
Pathway:
Tyrosine Kinase/Adaptors,Cytoskeletal Signaling,Apoptosis,Angiogenesis
Target:
FAK,FAK,Apoptosis,FAK