Bioactivity:

CHMFL-ABL/KIT-155 is a highly potent and orally active type II ABL/c-KIT dual kinase inhibitor (IC50s: 46 nM/75 nM). It arrests cell cycle progression and induces apoptosis.

CAS nr:

2081093-21-0

Purity:

98%

Molecular Weight:

609,68

SMILES:

O=C(N1CCC(OC2=CC(NC(C3=CC=C(CN4CCN(C)CC4)C(C(F)(F)F)=C3)=O)=CC=C2C)CC1)C5=CC=C(C)N=C5

Formula:

C33H38F3N5O3

Pathway:

Tyrosine Kinase/Adaptors

Target:

c-Kit