Bioactivity:

SMAP-2 is an orally bioavailable activator of phosphatase 2A (PP2A) which binds to the PP2A A_ scaffold subunit to drive conformational changes in PP2A. It inhibits the growth of KRAS-mutant lung cancers .

CAS nr:

1809068-70-9

Purity:

98%

Molecular Weight:

532,57

SMILES:

O=S(C1=CC=C(OC(F)(F)F)C=C1)(N[C@@H]2[C@@H](O)[C@H](N3C4=CC=CC=C4CCC5=CC=CC=C53)CCC2)=O

Formula:

C27H27F3N2O4S

Pathway:

Metabolism

Target:

Phosphatase