Bioactivity:

GNF362 is a selective and orally bioavailable inhibitor of inositol trisphosphate 3� kinase B (Itpkb; IC50: 9 nM). GNF362 also inhibits Itpka and Itpkc (IC50s: 20 nM and 19 nM).

CAS nr:

1003019-41-7

Purity:

98%

Molecular Weight:

426,44

SMILES:

N#CC1=CC=C(C=C1)C2=C(C=NN2)CN3C[C@H](N(CC3)C4=NC=C(C=C4)C(F)(F)F)C

Formula:

C22H21F3N6

Pathway:

Others

Target:

Others