Bioactivity:

RO-0335 is a potent diphenylether nonnucleoside reverse transcriptase inhibitor. RO-0335 inhibits Wt HIV-1 (IC50 = 1.1 nM) and retained activity (IC50< 100 nM) against 92% of a large number of NNRTI-resistant clinical isolates.

CAS nr:

867365-76-2

Purity:

98%

Molecular Weight:

573,22

SMILES:

NS(c(cc1)cc(Cl)c1NC(Cc(ccc(Br)c1Oc2cc(Cl)cc(C#N)c2)c1F)=O)(=O)=O

Formula:

C21H13BrCl2FN3O4S

Pathway:

Microbiology/Virology

Target:

Reverse Transcriptase