Bioactivity:

Momelotinib sulfate is an ATP-competitive JAK1/JAK2 inhibitor (IC50: 11 nM/18 nM). It has 10-fold selectivity versus JAK3.

CAS nr:

1056636-06-6

Purity:

98%

Molecular Weight:

610,62

SMILES:

O=C(NCC#N)C(C=C1)=CC=C1C2=NC(NC(C=C3)=CC=C3N4CCOCC4)=NC=C2.O=S(O)(O)=O.O=S(O)(O)=O

Formula:

C23H26N6O10S2

Pathway:

Angiogenesis,JAK/STAT signaling,Chromatin/Epigenetic,Stem Cells

Target:

JAK,JAK,JAK,JAK