Bioactivity:

Astragaloside IV, an active component isolated from Astragalus membranaceus, suppresses the activation of ERK1/2 and JNK, and downregulates matrix metalloproteases (MMP)-2, (MMP)-9 in MDA-MB-231 breast cancer cells. Astragaloside IV is a bioactive saponin

CAS nr:

84687-43-4

Purity:

98%

Molecular Weight:

784,99

SMILES:

CC(C)(O)[C@@H]1CC[C@@](C)(O1)[C@H]1[C@@H](O)C[C@@]2(C)[C@@H]3C[C@H](O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)[C@@H]4[C@]5(C[C@@]35CC[C@]12C)CC[C@H](O[C@@H]1OC[C@@H](O)[C@H](O)[C@H]1O)C4(C)C

Formula:

C41H68O14

Pathway:

Endocrinology/Hormones,Proteases/Proteasome,MAPK,MAPK

Target:

Estrogen/progestogen Receptor,MMP,JNK,ERK