Bioactivity:

Phleomycin is one of the anticancer glycopeptide antibiotics which cause DNA cleavage. It is similar to Bleomycin (HY-17565A) which binds and intercalates DNA to damage the integrity of the double helix.

CAS nr:

11006-33-0

Purity:

98%

Molecular Weight:

1268,29

SMILES:

NC1=NC(C(NCC(N)C(N)=O)CC(N)=N)=NC(C(NC(C(O[C@@]2(OC3[C@H](O)[C@@](O)(C(N)=O)[C@@H](O)C(CO)O3)[C@H](C)[C@@H](O)[C@H](O)[C@H](CO)O2)C4=CNC=N4)C(C(O)C(C)C(NC(C(C)=O)C(NCCC5=NC(C6=NC(C(N)=O)=CS6)CS5)=O)=O)=O)=O)=C1

Formula:

C48H69N17O20S2

Pathway:

Microbiology/Virology,Microbiology/Virology,Cell Cycle/Checkpoint,DNA Damage/DNA Repair

Target:

Antibacterial,Antibiotic,DNA/RNA Synthesis,DNA/RNA Synthesis