Bioactivity:

Bafilomycin A1 induces caspase-independent cell death in hepatocellular carcinoma cells via targeting of autophagy and MAPK pathways. Bafilomycin A1 is a vacuolar H+-ATPase inhibitor (IC50: 0.44 nM).�It is also found to inhibit autophagy while induces apo

CAS nr:

88899-55-2

Purity:

98%

Molecular Weight:

622,84

SMILES:

O[C@@]1(C[C@@H](O)[C@H](C)[C@H](O1)C(C)C)[C@@H](C)[C@H](O)[C@H](C)[C@H]2OC(=O)C(OC)=CC(C)=C[C@@H](C)[C@@H](O)[C@@H](C)CC(C)=CC=C[C@@H]2OC

Formula:

C35H58O9

Pathway:

Membrane transporter/Ion channel,Microbiology/Virology,Microbiology/Virology,Autophagy,Apoptosis

Target:

Proton pump,Antibacterial,Antibiotic,Autophagy,Apoptosis