TargetMol Chemicals

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APX-115 free base T10353

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Specifications

size	1mg/5mg/10mg/25mg/50mg/100mg

Bioactivity:

APX-115 free base (Ewha-18278 free base) is a potent, orally active pan NADPH oxidase _Nox) inhibitor (Kis: 1.08 _M, 0.57 _M, and 0.63 _M for Nox1, Nox2, and Nox4). APX-115 effectively prevents kidney injury.

CAS nr:

1270084-92-8

Purity:

98%

Molecular Weight:

279,34

SMILES:

CCCC1=C(NN(C1=O)C1=CC=CC=N1)C1=CC=CC=C1

Formula:

C17H17N3O

Pathway:

Immunology/Inflammation,Metabolism

Target:

NADPH-oxidase,NADPH