Bioactivity:

PIN1 inhibitor API-1 is a specific Pin1 inhibitor (IC50: 72.3 nM). PIN1 inhibitor API-1 retains the active conformation of pXPO5 and restores the ability of pXPO5 to transport pre-miRNAs from the nucleus to cytoplasm, thus up-regulating the anticancer miR

CAS nr:

680622-70-2

Purity:

98%

Molecular Weight:

366,3

SMILES:

C1=CC(=CC=C1CNC(=O)C(F)(F)F)COC2=NC(=NC3=C2NC=N3)N

Formula:

C15H13F3N6O2

Pathway:

Others

Target:

Others