Bioactivity:

Autogramin-1 potently inhibits autophagy induced by either mTORC1 inhibition (Rapamycin; IC50: 0.44 _M) or starvation (IC50: 0.17 _M).

CAS nr:

2375541-73-2

Purity:

98%

Molecular Weight:

485,56

SMILES:

O=C(N1)N(CCC)C(C2=C1C=C(C(NC3=NC(CCN(C(OC(C)(C)C)=O)C4)=C4S3)=O)C=C2)=O

Formula:

C23H27N5O5S

Pathway:

PI3K/Akt/mTOR signaling,Autophagy

Target:

mTOR,Autophagy