Bioactivity:

VER-155008 is a potent Hsp70 family inhibitor with IC50 of 0.5 _M, 2.6 _M, and 2.6 _M in cell-free assays for HSP70, HSC70, and GRP78, respectively, >100-fold selectivity over HSP90.

CAS nr:

1134156-31-2

Purity:

98%

Molecular Weight:

556,4

SMILES:

Nc1ncnc2n([C@@H]3O[C@H](COCc4ccc(cc4)C#N)[C@@H](O)[C@H]3O)c(NCc3ccc(Cl)c(Cl)c3)nc12

Formula:

C25H23Cl2N7O4

Pathway:

Endocrinology/Hormones,GPCR/G Protein,Metabolism,Cytoskeletal Signaling,Autophagy

Target:

GPR,GPR,HSP,HSP,Autophagy