Bioactivity:

GNE 5729 is an NMDAR of brain permeable positive allosteric modulator (EC50: 37 nM for GluN2A; 4.7 and 9.5 _M for GluN2C and GluN2D, respectively).

CAS nr:

2026635-66-3

Purity:

98%

Molecular Weight:

428,2

SMILES:

ClC1=C([C@H]2[C@H](C#N)C2)N3C(C=C1)=NC(CN4N=C(C(F)(F)F)C=C4Cl)=CC3=O

Formula:

C17H10Cl2F3N5O

Pathway:

Others

Target:

Others