Bioactivity:

KMH-233 is a potent selective LAT1 inhibitor 1 that inhibits the uptake of LAT1 substrate, L-leucine, and cell growth. Even at low concentrations (25 _M), it significantly enhanced the efficacy of betastatin and cisplatin.

CAS nr:

1941174-13-5

Purity:

98%

Molecular Weight:

587,6

SMILES:

O=C(O)[C@@H](N)CC1=CC=CC(C(NC2=C(C#N)C(C3=CC=C(OCC(NC)=O)C=C3)=C(C#N)C4=NC5=CC=CC=C5N24)=O)=C1

Formula:

C32H25N7O5

Pathway:

Target: