Bioactivity:

c-Fms-IN-6 is a potent inhibitor of c-FMS (IC50 ﾲ10 nM for unphosphorylated c-FMS) and also weakly inhibits unphosphorylated c-KIT and PDGFR (IC50: > 1 _M).

CAS nr:

1628574-81-1

Purity:

98%

Molecular Weight:

419,48

SMILES:

O=C1N(C2=NC(C)=C(OC3=CC(C4=CN(CC)N=C4)=NC=C3)C=C2)N=C(C(C)(C)C)N1

Formula:

C22H25N7O2

Pathway:

Tyrosine Kinase/Adaptors

Target:

c-Fms