Bioactivity:

Shizukaol B exerts anti-inflammatory effects in LPS-activated microglia partly by modulating JNK-AP-1 signaling pathway; it also shows significant anti-neuroinflammatory effects by inhibiting nitric-oxide (NO) production in lipopolysaccharide (LPS)-stimul

CAS nr:

142279-40-1

Purity:

98%

Molecular Weight:

732,77

SMILES:

COC(=O)C(\C)=C1\[C@H]2C3=C(C[C@H]4[C@@]5(C)[C@@H]6C[C@@H]6[C@@]6(O)COC(=O)\C(C)=C\COC(=O)CCC(=O)OCC7=C(C[C@H]56)[C@@]24OC7=O)[C@H]2C[C@H]2[C@]3(C)[C@@H](O)C1=O

Formula:

C40H44O13

Pathway:

Immunology/Inflammation,Apoptosis,Immunology/Inflammation,MAPK,Proteases/Proteasome,Microbiology/Virology,GPCR/G Protein,NF-_b,MAPK,Neuroscience,Immunology/Inflammation,DNA Damage/DNA Repair,Cell Cycle/Checkpoint,Immunology/Inflammation,MAPK

Target:

NOS,TNF,Prostaglandin Receptor,JNK,HIV Protease,HIV Protease,Prostaglandin Receptor,NF-_B,p38 MAPK,COX,COX,DNA/RNA Synthesis,DNA/RNA Synthesis,IL Receptor,ERK