Bioactivity:

Lanraplenib monosuccinate inhibits SYK activity in platelets via the glycoprotein VI (GPVI) receptor without prolonging bleeding time (BT) in monkeys or humans.�Lanraplenib monosuccinate �is a highly selective and orally active SYK inhibitor (IC50=9.5 nM)

CAS nr:

1800046-97-2

Purity:

98%

Molecular Weight:

561,59

SMILES:

NC1=CN=CC(C2=CN3C(C(NC4=CC=C(N5CCN(C6COC6)CC5)C=C4)=N2)=NC=C3)=N1.O=C(O)CCC(O)=O

Formula:

C27H31N9O5

Pathway:

Tyrosine Kinase/Adaptors,Angiogenesis

Target:

Syk,Syk