Bioactivity:

G150 inhibited interferon expression triggered by DSDNA with IC50 of 10.2 nM.G150 is an effective and highly selective inhibitor of human cyclic GMP-AMP synthase (H-CGAS).

CAS nr:

2369751-30-2

Purity:

98%

Molecular Weight:

391,25

SMILES:

Nc(cc1)ncc1-c(c1c2[nH]c(CC3)c1CN3C(CO)=O)cc(Cl)c2Cl

Formula:

C18H16Cl2N4O2

Pathway:

DNA Damage/DNA Repair,Immunology/Inflammation

Target:

DNA,cGAS