Bioactivity:

Ingenol mebutate shows anticancer activity, and P-gp-mediated absorptive transport, dermal penetration, and vascular damage contribute to the anticancer activity of ingenol-3-angelate in vivo; it activates a broad range of PKC isoforms and induces apoptos

CAS nr:

75567-37-2

Purity:

98%

Molecular Weight:

430,53

SMILES:

C[C@H](C[C@H]1C(C)(C)[C@H]1[C@@H]1C=C(CO)[C@H]([C@@]2([C@H](C(C)=C3)OC(/C(/C)=C\C)=O)O)O)[C@]23C1=O

Formula:

C25H34O6

Pathway:

Immunology/Inflammation,Microbiology/Virology,Proteases/Proteasome,Cytoskeletal Signaling,Chromatin/Epigenetic

Target:

gp120/CD4,HIV Protease,HIV Protease,PKC,PKC