Bioactivity:

RO-3306 is a selectivity ATP-competitive CDK1 inhibitor (Ki: 20 nM). The selectivity of RO-3306 for CDK1 is >15-fold higher than a diverse panel of human kinases.

CAS nr:

872573-93-8

Purity:

98%

Molecular Weight:

351,45

SMILES:

O=C1N=C(NCc2cccs2)S\C1=C/c1ccc2ncccc2c1

Formula:

C18H13N3OS2

Pathway:

Cytoskeletal Signaling,Tyrosine Kinase/Adaptors,Metabolism,Apoptosis,Chromatin/Epigenetic,Cell Cycle/Checkpoint,MAPK

Target:

PKC,PKA,SGK,Apoptosis,PKC,CDK,ERK