Bioactivity:

Agnuside inhibits COX-2 (IC50: 0.026 mg/ml) but exhibits less than 10% inhibition of COX-1 at this concentration. It also inhibits 46.3, 66.8, and 82.1% of P-glycoprotein (P-gp) ATPase activity at concentrations of 5, 25, and 100 _M, respectively.

CAS nr:

11027-63-7

Purity:

98%

Molecular Weight:

466,44

SMILES:

OC[C@H]1O[C@@H](O[C@@H]2OC=C[C@H]3[C@H](O)C=C(COC(=O)c4ccc(O)cc4)[C@@H]23)[C@H](O)[C@@H](O)[C@@H]1O

Formula:

C22H26O11

Pathway:

GPCR/G Protein,Immunology/Inflammation,Neuroscience,Membrane transporter/Ion channel,Neuroscience,Immunology/Inflammation

Target:

Prostaglandin Receptor,Prostaglandin Receptor,P-gp,P-gp,COX,COX