YKL-05-099 T17271
Specifications
| 1mg/5mg/10mg/25mg/50mg/100mg |
Bioactivity:
YKL-05-099 is an inhibitor of the salt-inducible kinase(SIK1 and SIK3 ; IC50s: 10 and 30 nM, respectively). It has a slightly less potent SIK2-inhibitory (IC50:40 nM).
CAS nr:
1936529-65-5
Purity:
98%
Molecular Weight:
600,11
SMILES:
CC1=C(C(=CC=C1)Cl)N2CC3=CN=C(N=C3N(C2=O)C4=NC=C(C=C4)OC)NC5=C(C=C(C=C5)C6CCN(CC6)C)OC
Formula:
C32H34ClN7O3
Pathway:
PI3K/Akt/mTOR signaling
Target:
SIK
