PBIT T16435
Specifications
| 1mg/5mg/10mg/25mg/50mg/100mg |
Bioactivity:
PBIT inhibits JARID1B histone demethylase (IC50 of about 3 _M). PBIT also inhibits JARID1A and JARID1C (IC50s of 6 _M and 4.9 _M, respectively). PBIT is a specific inhibitor of the Jumonji AT-rich Interactive Domain 1 (JARID1) enzymes .
CAS nr:
2514-30-9
Purity:
98%
Molecular Weight:
241,31
SMILES:
O=C1N(C2=CC=C(C)C=C2)SC3=C1C=CC=C3
Formula:
C14H11NOS
Pathway:
Chromatin/Epigenetic,Chromatin/Epigenetic
Target:
Histone Methyltransferase,Histone Demethylase
