Bioactivity:

AMG-1 is a potent inhibitor of human RON and c-Met.In vitro�kinase assays showed that compound I is a potent inhibitor of human RON and c-Met with IC50s of 9 and 4 nmol/L, respectively.

CAS nr:

913376-84-8

Purity:

98%

Molecular Weight:

556,58

SMILES:

CC(C)(CN(C(C)=C(C(Nc(cc1)cc(F)c1Oc1ccnc2cc(OC)ccc12)=O)C1=O)N1c1ccccc1)O

Formula:

C31H29FN4O5

Pathway:

Tyrosine Kinase/Adaptors

Target:

c-Met/HGFR