Bioactivity:

Eupatolide has anti-inflammatory activity, it inhibits lipopolysaccharide-induced COX-2 and iNOS expression in RAW264.7 cells by inducing proteasomal degradation of TRAF6. It can suppress PDGF-induced proliferation and migration of VSMC through HO-1 induc

CAS nr:

6750-25-0

Purity:

98%

Molecular Weight:

248,32

SMILES:

C\C1=C/CC\C(C)=C\[C@H]2OC(=O)C(=C)[C@@H]2[C@H](O)C1

Formula:

C15H20O3

Pathway:

Angiogenesis,Tyrosine Kinase/Adaptors,Immunology/Inflammation,Immunology/Inflammation,Immunology/Inflammation,Apoptosis,GPCR/G Protein,Immunology/Inflammation,MAPK,Cytoskeletal Signaling,PI3K/Akt/mTOR signaling,NF-_b,Neuroscience,Immunology/Inflammation,Autophagy,DNA Damage/DNA Repair,Cell Cycle/Checkpoint

Target:

PDGFR,PDGFR,NOS,Nrf2,ROS,TNF,Prostaglandin Receptor,Prostaglandin Receptor,MAPK,Akt,Akt,NF-_B,COX,COX,Autophagy,DNA/RNA Synthesis,DNA/RNA Synthesis