Bioactivity:

PF-06372222 is a small-molecule negative allosteric modulator of the glucagon receptor (GCGR). PF-06372222 is also an antagonist for glucagon-like peptide-1 receptor GLP-1R, which inhibits glucagon secretion and glucose-dependent insulin secretion.

CAS nr:

1407592-99-7

Purity:

98%

Molecular Weight:

515,54

SMILES:

FC(F)(F)C1=CN(C2=CC=C(N[C@@H](C3=CC=C(C(NCCC(O)=O)=O)C=C3)C4CC(C)(C)C4)C=N2)C=N1

Formula:

C26H28F3N5O3

Pathway:

Target: