Bioactivity:

CK1-IN-1, compound 1c reported in patent WO2015119579A1, is a casein kinase 1 (CK1) inhibitor. It has IC50s of 15 nM, 16 nM, 73 nM for CK1_, and CK1_, p38_ MAPK, respectively.

CAS nr:

1784751-20-7

Purity:

98%

Molecular Weight:

383,39

SMILES:

Fc1ccc(cc1)-c1nc([nH]c1-c1ccncc1)-c1ccc2ccccc2c1F

Formula:

C24H15F2N3

Pathway:

MAPK,Stem Cells,Metabolism

Target:

p38 MAPK,Casein Kinase,Casein Kinase