Bioactivity:

JHU-083 is a selective glutaminase antagonist. JHU-083 blocks glutaminase activity in brain CD11b+ cells. JHU-083 also experimental cerebral malaria (ECM) resulting in a net decrease of glutamate levels in the animals.

CAS nr:

1998725-11-3

Purity:

98%

Molecular Weight:

312,36

SMILES:

O=C(OCC)[C@H](CCC(C=[N+]=[N-])=O)NC([C@H](CC(C)C)N)=O

Formula:

C14H24N4O4

Pathway:

Others

Target:

Others