Bioactivity:

SB 224289 is a selective antagonist of 5-HT1B receptor with pKi of 8.2. It is a centrally active following oral administration in vivo. SB 224289 displays 60-fold selectivity over 5-HT1D, 5-HT1A, 5-HT1E, 5-HT1F, 5-HT2A and 5-HT2C receptors in radioligand

CAS nr:

180083-23-2

Purity:

98%

Molecular Weight:

520,63

SMILES:

O=C(N1CCC2=C1C=C3C(OCC34CCN(C)CC4)=C2)C5=CC=C(C6=CC=C(C7=NOC(C)=N7)C=C6C)C=C5

Formula:

C32H32N4O3

Pathway:

Target: