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Bioactivity:
Rucaparib is an inhibitor of PARP with Ki of 1.4 nM for PARP1 in a cell-free assay, and also shows binding affinity to eight other PARP.
CAS nr:
283173-50-2
Purity:
98%
Molecular Weight:
323,36
SMILES:
CNCc1ccc(cc1)-c1[nH]c2cc(F)cc3C(=O)NCCc1c23
Formula:
C19H18FN3O
Pathway:
DNA Damage/DNA Repair,Chromatin/Epigenetic
Target:
PARP,PARP