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Bioactivity:
GNE684 is a potent inhibitor of receptor-interacting protein 1 (RIP1; (mean Kiapps: 21 nM, 189 nM, and 691 nM for human, mouse, and rat RIP1).
CAS nr:
T11442
Purity:
98%
Molecular Weight:
432,48
SMILES:
COC1=NC=C(N(C)C([C@@H](NC(C2=NN([C@H](C3=CC=CC=C3)CC4)C4=N2)=O)CC5)=O)C5=C1
Formula:
C23H24N6O3
Pathway:
Apoptosis
Target:
TNF